Thursday, February 20, 2025

The ABC of Immunology (5)

Very rarely,
The Sun and The Moon
influence our immunity 

people realise that our immunity 
is closely tied to 
the day and night!

In other words,
if we do not follow 
the law of the Sun and the Moon, 
very likely we will have compromised immunity.

Mainly, it's due to 
the unTIMEly rest and stress.

(a) Untimely Rest 

This refers to 
sleeping/resting too much 
during the day or 
waking up too late 
in the morning (1hr after sunrise). 

During day time, 
our body is designed to operate mainly 
in sympathetic nervous mode
when Th2 Immunity (or Extracellular Immunity) predominates. 

When we sleep/rest too much during the day, 
our body switches to parasympathetic nervous mode too frequently, 
rendering the extracellular  defence compromised 
(due low immuno metabolism).
We will then tend to get immuno-suppressive type of diseases.

(b) Untimely Stress

This refers to 
working very hard after sundown, 
sleeping late, 
stress-induced poor quality sleep/insomnia.

After sundown, 
our body goes into parasympathetic nervous mode 
to activate Th1 immunity (intracellular immunity). 

If we engage with work stress 
or physical stress (including rigorous exercise)
during evening time, 
our body will switch back 
to sympathetic nervous mode,
compromising Th1 immunity
which is important to fight
viral, parasitic infection and cancers.

When Th1 dominates the day time 
(while it should have been Th2 by default), 
due to resting too much,
one tends to get immune disorders like:
Multiple Sceloris
Rheumatoid Arthritis 
Irritable Bowel Disease


When Th2 dominates the night time 
(while it should have been Th1 by default), 
due stress after sundown/overnight
one tends to get immune disorders like:
Allergies
Systemic Lupus Erythematosus 
Cancer

Therefore, 
in order to have a healthy immune system,
other than diet,
we also ought to watch over our lifestyle.

Work-Life balance 
ensuring we don't work after sundown
can help us wade off or recover from viral infection and cancers.

Keeping ourselves aspired and motivated
will reduce the chance of 
over-relaxation during the day,
and reduce chance of organ-specific autoimmune disorders.

Yet in another post to come, we will discuss how immunity sometimes can be hijacked leading to life risking tragedy.

Meanwhile, 
let's learn to live by the Rhythm of 
the Sun and the Moon.

Well wishes,
Kee Yew

#immunology #Th1 #Th2 #cancer #autoimmunity


{Learning Holistic Wellness for Wisdom and Compassion}

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